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Shifting architectures of cognition and brain function in younger and older adults

What is this Study about?

Thinking skills (also known as cognitive functions), change from younger to older adulthood. In this study we are investigating how these shifting architectures of cognition and brain function relate to one another, and how these brain and cognitive changes impact decision-making in younger and older adults.

You may qualify to participate if you are: 1) 60 years of age or older, 2) right-handed, 3) in good health, 4) and have normal or corrected-to-normal vision. Participation will involve completing cognitive tasks, questionnaires, and non-invasive brain measurements using MRI. If you are interested in participating in this study, please contact lbc.spreng@gmail.com

What Will Happen in This Study?

This study will take place on 3 separate days for a total of 14 hours of participation.

Day 1: Participants will be invited to the laboratory to complete 2.5 hours of computer tasks as well as an undergo a 2-hour long MRI (i.e., magnetic resonance imaging) scan.

Day 2: Participants will return to the lab for another 2.5 hours of cognitive testing, including neuropsychological questionnaires. They will then undergo another 2-hour long MRI scan.

Day 3: Participants will undergo a 45-min long MEG (i.e., magnetoencephalography) scan, a blood draw, and some behavioural tests, for a total of 3 hours.

Who is Eligible to Participate in this Study?

You are eligible to participate if you:

- Are aged 60 years or older

- Are right-handed

- Are cognitively healthy

- Are able to come in-person to our site, located at the Montreal Neurological Institute

- Have no metal in your body (e.g., pacemaker, metal plates, orthopedic devices, etc.)

- Speak English or French

Get in Touch About this Study

Legal Disclaimer

Any materials or links provided herein are strictly for informational purposes only. The Alzheimer Society of Canada does not endorse nor recommend any of the manufacturers, products or institutions mentioned in any of these links or listings as suitable or appropriate for your particular situation or circumstances and disclaims any liability with respect to representations, warranties, including fitness for an intended particular use or purpose, and all other claims relating thereto, all of which remain strictly with the manufacturer or institution.

In no event shall the Alzheimer Society of Canada or any third parties mentioned on the website be liable for any damage (including, without limitation, incidental and consequential damages for personal injury/wrongful death, lost profits or damages resulting from lost data or business interruption) or personal injury (including death) resulting from the use, misuse or inability to use any activity, product or service mentioned herein, whether based in warranty, contract, tort or any other legal theory.

Everyone considering participating in any activity is encouraged to speak with their own doctor or health-care team before participating in any activity that may impact their health or well-being.

Observational Study

Target Population

Healthy volunteers, Caregivers

Target Age Group(s)

41-65

Study Location

In-Person

Quebec

Montreal Neurological Institute, Montreal

Quebec

Study Contact

Ting Ting Liu
Research Assistant
McGil University

Recruitment Start Date

July 7, 2025

Recruitment End Date

September 26, 2026
  • Learn more about observational studies
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Alzheimer Society of Canada
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Toronto, Ontario M4R 1K8
Information and Referral Line: 1-855-705-4636
Email: research@alzheimer.ca

Charity registration number: 11878 4925 RR0001

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