Selecting one or more of the options below will update the content below.

Age Group
Type of Study
Study Format
Location
Target Population
  • Observational Study
    Online

    What is this Study about?

    Behavioral and emotional changes often accompany dementia and are a leading cause of long-term care placement, even more so than cognitive decline. This study is the first to explore how family caregivers make treatment decisions in response to these emotional and behavioural symptoms. We are interested in understanding whether caregivers turn to medications, consider non-pharmacological strategies such as environmental modifications, or use a combination of both. Using a quantitative behavioural economics model, this study will examine how caregivers weigh the risks and benefits of different treatment options. We are particularly interested in decision-making related to dopaminergic medications (formerly known as “antipsychotics”), which are commonly prescribed despite known risks for people with dementia. The information gathered will help guide the development of resources to better support family caregivers in navigating treatment decisions. Participation involves completing an anonymous online survey and is open to family caregivers involved in medical decision-making for a relative or close friend with dementia.

    Eligibility Criteria

    Participants will consist of caregivers of individuals with dementia who meet the following eligibility criteria:

    Participants must be at least 18 years old,
    Participants must be able to read English fluently,
    Participants must be a family caregiver (partner, spouse, family member, or close friend) of a
    person with dementia
    Participants must be involved in the medical decision-making for the person with dementia,
    Participants must have access to a desktop computer, laptop, or another device with a physical keyboard and mouse/trackpad,
    Participants must not be a professional healthcare provider (e.g., physician, nurse, certified nursing assistant).

    Additionally, the person with dementia whom they are assisting must be community-dwelling (i.e., they cannot be residing in a residential or skilled nursing facility).

    Recruitment End Date

  • Observational Study
    In-Person and Online

    What is this Study about?

    Participants will take part in a one-on-one interview (in person or online) to share thoughts on reminders and changes in behavior that should be tracked by the system. Interviews will last about 60 minutes. A short follow-up (20 minutes or less) may also be requested later to provide extra feedback on the system’s design.

    Eligibility Criteria

    You are eligible to participate if you:

    - Are an informal caregiver of a person living with dementia
    - Provide at least 30 hours of care per week
    - Speak and understand English
    - Are able to give informed consent
    - (Optional) The person you care for may also join if eligible
     

    Recruitment End Date

  • Observational Study
    In-Person and Online

    What is this Study about?

    This study is testing a digital reminder system for people living with dementia. The system sends alerts when daily routines change and collects feedback from caregivers. The goal is to improve the system’s design and usefulness. Results will help make reminder tools more supportive for people living with dementia and their caregivers.

    Eligibility Criteria

    You are eligible to participate if you are a person living with dementia and you:
    - Have a clinical diagnosis of mild to moderate dementia
    - Were diagnosed within the past 2 years
    - Speak and understand English
    - Are able to give informed consent
    - Have internet access at home
    - Are part of a caregiver-participant pair (dyad)

    You are eligible to participate if you are a caregiver and you:
    - Are an informal caregiver (family member or friend)
    - Provide at least 30 hours of care per week to a person living with dementia
    - Speak and understand English
    - Are able to give informed consent
    - Can participate in a home setup session and follow-up interview

    Recruitment End Date

  • Observational Study
    Online

    What is this Study about?

    The purpose of this study is to examine the effect of CARES-D for physiotherapists on learner knowledge, attitudes, and confidence in dementia. We will administer online questionnaires to practicing rehabilitation professionals in Canada who work with individuals with dementia to: 1) Assess changes in rehabilitation professionals' knowledge about dementia; 2) Evaluate shifts in attitudes toward individuals with dementia; 3) Measure improvements in confidence in managing dementia care; 4) Gather participant feedback on the CARES-D training program; 5) Compare pre- and post-training outcomes to determine the program's effectiveness.

    Eligibility Criteria

    - Are a practicing physiotherapist, occupational therapist, physiotherapy assistant, occupational therapy assistant or kinesiologist with a minimum of 6 months of experience.
    - Work with individuals living with dementia, regardless of the setting
    - Work anywhere in Canada
    - Fluent in English

    Recruitment End Date

  • Clinical Trial
    In-Person

    What is this Study about?

    We are conducting three separate studies to explore the effects of transcranial Direct Current Stimulation (tDCS) in individuals with Alzheimer’s Disease or Primary Progressive Aphasia. tDCS is a non-invasive therapy that uses low electrical currents to stimulate specific areas of the brain. Previous research has suggested that tDCS can improve symptoms such as language difficulties and may help slow the progression of Alzheimer’s.

    Our studies aim to investigate these effects in different contexts, including language therapy and overall mental abilities. Upon completion, participants will receive their study results to help guide their decisions about whether tDCS could be part of a long-term therapy plan.

    Eligibility Criteria

    Person living with Alzheimer's disease

    Recruitment End Date

  • Observational Study
    Online

    What is this Study about?

    The objective of this study is to understand: (1) what community-based interventions caregivers/care partners for persons living with young onset dementia (i.e., dementia diagnosed under the age of 65) are accessing across Southern Ontario; (2) caregivers/care partners perceptions towards the community-based interventions they have accessed; and (3) the reasons, if any, for not accessing community-based interventions.

    The results of this study will be used to help inform the development and enhancement of community-based interventions for persons living with YOD and their caregivers/care partners, and is a part of my PhD dissertation.

    Eligibility Criteria

    To participate you must:

    -be a family caregiver or care partner to a person living with young onset dementia OR

    were a family caregiver/care partner to a person living with young onset dementia within

    the past six months

    -be 18 years or older

    -live within Southern Ontario

    Recruitment End Date

  • Clinical Trial
    In-Person

    What is this Study about?

    The purpose of this study is to measure the difference in time to developing or worsening memory, thinking, or functional problems due to Alzheimer's disease occurring in participants receiving study drug compared to placebo.

    Participation could last up to 255 weeks including screening, a double-blind treatment period, and a double-blind observation period. In addition, eligible participants who receive placebo during the double-blind treatment period may choose to extend their study participation to receive open-label remternetug in an extension period.

    Eligibility Criteria

    Male or female participants aged 65 to 80 years of age 
    Minimal to no cognitive/functional impairment at Screening
    Must have a study partner

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    The study involves a primary session of paper-and-pencil tasks, and a second session of a computer task, while your heart rate and brain activity is monitored. The aim of the study is to examine how signals are affected from the body to the brain.

    Eligibility Criteria

    - You are between the ages of 18-30 or 60-85

    - Free from conditions (other than amnestic mild cognitive impairment (aMCI)) which affect cognition or cardiac health

    - Fluent in the English language

    - Have normal or corrected-to-normal vision

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    Increasing evidence shows that listening to music from childhood and early adulthood can help recall meaningful events from the past. Importantly, people with dementia have shown to benefit from listening to personally meaningful music, suggesting that musical memory remains preserved. However, the underlying mechanisms by which music improves memory remains unclear.

    My research addresses the impact of an autobiographically salient music listening program on memory and brain activity in mild cognitive impairment. Understanding how brainwave activity in this population may differ, will help elucidate mechanisms of music listening that lead to cognitive improvements, ultimately providing insight into musical memory preservation and how it can be leveraged.

    Participants will undergo cognitive testing and measure brainwave activity via EEG, a non-invasive neuroimaging method. Participants will be provided an online link (or CD if they do not have wifi) to access their personalized music playlist and will be asked to listen for two weeks at home (20 mins/day, minimum 5 days/wk). Repeated cognitive and EEG assessment will help determine changes in brain function.

    Eligibility Criteria

    - are 60 years of age and over

    - have received a diagnosis of mild cognitive impairment

    - are English speaking

    - have a minimum of high school education

    - have adequate hearing and vision

    - can identify 15 English vocal/lyrical songs that are associated to your personal memories

    - can commit to listening to your personal playlist (20 mins) at-home for 2 weeks (minimum 5 days/week)

    Recruitment End Date