The Alzheimer Society Research Portal connects researchers with Canadians looking to participate in research studies. On this website, find active studies that you can participate in to help advance research on dementia.
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Selecting one or more of the options below will update the content below.
- Observational StudyIn-Person
What is this Study about?
The study involves a primary session of paper-and-pencil tasks, and a second session of a computer task, while your heart rate and brain activity is monitored. The aim of the study is to examine how signals are affected from the body to the brain.
Eligibility Criteria
- You are between the ages of 18-30 or 60-85
- Free from conditions (other than amnestic mild cognitive impairment (aMCI)) which affect cognition or cardiac health
- Fluent in the English language
- Have normal or corrected-to-normal vision
Recruitment End Date
- Clinical TrialOnline
What is this Study about?
Scientific evidence indicates that healthy lifestyle habits promote brain health and help prevent Alzheimer’s disease.
Our study consists of evaluating a personalized program designed to promote healthy lifestyle habits with the goal of supporting brain health.
This program, called Luci, is available as an online platform with virtual guidance from an advisor. Its purpose is to help participants change their lifestyle habits. It focuses on three areas: physical activity, healthy eating, and intellectual stimulation.
The aim of this study is to determine whether our program helps improve lifestyle habits in these three areas, along with other indicators linked to brain health.
Eligibility Criteria
You are eligible to participate if you:
• Are aged between 50 and 75 years of age
• Have not been diagnosed with a cognitive disorder, such as Alzheimer’s disease
• Wish to adopt healthy lifestyle habits in at least one of the following domains: physical activity, healthy eating, and intellectual stimulation
• Have access to a tablet or computer with an internet connection
• Are able to speak English or French
Recruitment End Date
- Observational StudyOnline & In-Person
What is this Study about?
We are interested in how the brain changes in aging and with dementia. With this study, we will investigate how the brain senses and interprets sights and sounds. We are particularly interested in how listening to music, especially familiar music, evokes emotions and activates vivid memories. Learning how the brain processes music will help us understand why music therapy is such an effective tool for those with Alzheimer’s. We also aim to understand how the brain combines sights and sounds. This is an important part of how we navigate complex everyday situations, such as walking down a busy street. Alzheimer’s disease interferes with the brain’s ability to combine information from different senses, which could cause challenges in daily living.
Eligibility Criteria
You are eligible to participate in this study if you are:
- A healthy young adult aged 18-35, a healthy older adult aged 65 and up, or an older adult with mild/early-stage dementia as diagnosed by your doctor
- Able to provide written, informed consent to participate
- Have normal or corrected-to-normal hearing in both ears and vision in both eyes
- You must have no history of cerebro-vascular injury or accident (such as a stroke)
- For adults without dementia, you must have no known neurological conditions and must not be taking any neuroactive drugs
You will not be eligible to participate in the study if you:
- Have metallic objects that cannot be removed for the MEG recording (such as permanent piercings and medical implants that are made from magnetic metals)
- Are pregnant
- Feel you cannot perform the audio-visual and/or music listening tasks
Recruitment End Date
- Observational StudyOnline
What is this Study about?
CAN-PROTECT is a Canada-wide online study recruiting participants and caregivers of persons with dementia to explore how lifestyle, background, and caretaking factors affect our health, quality of life, cognition, behaviour, and function as we age. CAN-PROTECT data will be analyzed and jointly published by the University of Calgary in partnership with the University of Exeter.
Eligibility Criteria
- Age 18 years or older
- Reside in Canada
- Have access to a computer/touchscreen device
- Can provide informed consent
- Do not have a diagnosis of dementia
- Additionally, we are enrolling participants who have previously or currently care for persons with dementia for caregiver-specific assessments
- Ability to speak English
Recruitment End Date
- Observational StudyIn-Person
What is this Study about?
Our study titled "Investigating the Role of Quantitative Susceptibility Mapping and Oxygen Extraction Fraction as Advanced Neuroimaging Biomarkers in Alzheimer's Disease" aims to develop non-invasive diagnostic biomarkers for Alzheimer's Disease (AD). We focus on evaluating the potential of QSM and OEF to differentiate between AD, Mild Cognitive Impairment (MCI), and Cognitively Unimpaired populations and to predict amyloid and tau pathology, using a Systems Biology approach. Leveraging the McGill University's TRIAD cohort, the study utilizes advanced imaging and machine learning to predict amyloid and tau presence, which could transform AD diagnostics and treatment. Methodologically, it involves preprocessing neuroimaging data and employing machine learning classifiers to analyze these features. The anticipated outcomes include validating QSM and OEF as non-invasive biomarkers for AD, establishing their correlation with amyloid and tau proteins, and developing predictive models for clinical decision-making, potentially resulting in significant advancements in AD diagnostics.
Eligibility Criteria
Are a member of the TRIAD cohort at McGill University, falling within one of the following categories: young control, cognitively unimpaired, mild cognitive impairment, or Alzheimer's Disease.
Are willing and able to undergo advanced neuroimaging techniques including MRI and PET without contraindications.
Have not had any significant neurological conditions (other than AD for the AD group) that might interfere with the results of the study.
Have no metal implants, devices, or other conditions that may contraindicate or distort MRI imaging.
Are not currently participating in other clinical trials or studies that involve interventions which might interfere with the results of this study.
Are able and willing to provide informed consent for participation in the study or have a legally authorized representative who can do so.
Do not have a history of substance abuse or other conditions that might confound the imaging and cognitive data.
Have not undergone any significant head trauma or surgery in the past 6 months.
Are not pregnant or planning to become pregnant during the duration of the study.
Are willing to comply with all study-related procedures, imaging sessions, and follow-up evaluations.
Ability to speak English and French
Recruitment End Date
Alzheimer Society of Canada
20 Eglinton Avenue West, 16th Floor
Toronto, Ontario M4R 1K8
Information and Referral Line: 1-855-705-4636
Email: research@alzheimer.ca
Charity registration number: 11878 4925 RR0001
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