The Alzheimer Society Research Portal connects researchers with Canadians looking to participate in research studies. On this website, find active studies that you can participate in to help advance research on dementia.
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- Observational StudyOnline
What is this Study about?
This study looks at how an at-home nature-based virtual reality (VR) program may help people living with Alzheimer’s disease manage behavioural and psychological symptoms of dementia (BPSD), such as depression. Caregivers/study partners will have the option of taking part in the study and providing feedback regarding the VR intervention. This project will explore how VR can be used as a non-pharmacological approach to prolong aging in place for individuals with BPSD, as BPSD contributes to rates of institutionalization. This will take place completely remotely, in your own home.
Eligibility Criteria
AD-D Participant Inclusion Criteria:
1) Clinical diagnosis of mild to early-moderate stage AD (including mixed dementia with AD) using the Diagnostic and Statistical Manual of Mental Disorders, 5th Ed. Criteria (29)
2) Age of 50 years or older
3) Medical stability to participate in the trial
4) Patient Health Questionnaire score 5-14
5) Investigator judgement on whether the participant is comfortable with technology
6) Access to WiFi and a smart device for connecting on WebEx and downloading the Fitbit and Muse applications
7) Have someone available to be present during all sessions
Caregiver Inclusion Criteria:1) 18 years of age or older
2) Available to be present for all sessions
3) Ability to provide consent
4) Access to a smart device
Caregiver Exclusion Criteria:
1) Under 18 years of age
Recruitment End Date
- Observational StudyOnline & In-Person
What is this Study about?
In collaboration with our South Asian community collaborators, our goal is to gain an in-depth understanding of new immigrant, multigenerational, South Asian family caregiving for a relative with dementia amidst COVID-19. The goal is to inform future family-centered, healthcare interventions aimed at supporting equity deserving families during times of crisis.
To achieve our goal, we are starting to recruit family care partners living in a multigenerational home and caring for a relative with dementia from each of the four groups of South Asian families. We will be using a multiple case study to examine new immigrant, multigenerational caregiving for a relative with dementia from the perspective of four groups of South Asian families; 1) Pakistani, 2) Bangladeshi, 3) Indian, and 4) Sri Lankan. We will also be using secondary data sources, including genograms, ecoMaps, and key documents.
We will be conducting interviews with a family care partners from each of the four groups. Following these interviews, we will hold four focus groups with a new purposeful sample of South Asian multigenerational care partners to understand if the findings from the interviews reflect their caregiving experiences thereby increasing the reliability of the study findings.
Eligibility Criteria
You are eligible if
1. You are caring for a family member or relative with memory loss or dementia
2. You are living in a multigenerational South Asian Family
3. You Identify with any of these four South Asian Countries: India, Pakistan, Bangladesh and Sri Lanka
4. You live in the Greater Toronto Area (GTA)
Recruitment End Date
- Observational StudyOnline & In-Person
What is this Study about?
The aim of this study is to develop a large, ethically sources, and diverse database of voice recordings to determine whether voice has biomarkers for particular disease categories, including neurological and neurodevelopmental conditions. The data that is collected will be used to develop a full open-access database to fuel artificial intelligence research related to voice.
Eligibility Criteria
- Between ages of 44-85
- Able to read, write, speak, and understand English
- Be diagnosed with one of the following conditions:
- Alzheimer’s disease
- Parkinson’s disease
- Amyotrophic Lateral Sclerosis
- Mild Cognitive Impairment, or other types of dementia
- Consent to provide a voice/speech sample
Recruitment End Date
- Clinical TrialOntario
What is this Study about?
McMaster University, in partnership with Ressam Gardens Memory Care Community, is conducting a study on the effects of brain stimulation in individuals aged 50 and older with dementia or memory loss. The research focuses on using repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique that delivers magnetic pulses to the brain, to enhance cognitive function and balance. The goal is to extend the positive effects of brain stimulation in improving cognition and balance in individuals with dementia.
Eligibility Criteria
You are eligible to participate if you…
1.) Diagnosed with Dementia and/or memory loss by a clinician
2.) Exhibit adequate oral communication skills and cognitive function sufficient to obtain a score ranging between 10-27 on the Mini-Mental State Exam
3.) Walk or stand with or without personnel or assistive devices
4.) Individuals must be greater than or equal to 50 years of age
Recruitment End Date
- Observational StudyOnline
What is this Study about?
In this study we aim to explore the motivations and impacts of disclosure a personal diagnosis of dementia or being a care partner on social media. The overall goal of the study is to develop an evidence-based resource to promote benefits of social media for the dementia community while minimizing its harms.
Eligibility Criteria
-Identify as an individual living with dementia
-Identify as a care partner
-Are over the age of 19
-Have posted on social media about living with dementia or being a care partner
-Speak English
If you are interested in participating, please contact mallorie.tam@ubc.ca or sign up using the following link: https://ubc.ca1.qualtrics.com/jfe/form/SV_5nGjQ2K27SEZwOi
Recruitment End Date
- Observational StudyOnline
What is this Study about?
CAN-PROTECT is a Canada-wide online study recruiting participants and caregivers of persons with dementia to explore how lifestyle, background, and caretaking factors affect our health, quality of life, cognition, behaviour, and function as we age. CAN-PROTECT data will be analyzed and jointly published by the University of Calgary in partnership with the University of Exeter.
Eligibility Criteria
- Age 18 years or older
- Reside in Canada
- Have access to a computer/touchscreen device
- Can provide informed consent
- Do not have a diagnosis of dementia
- Additionally, we are enrolling participants who have previously or currently care for persons with dementia for caregiver-specific assessments
- Ability to speak English
Recruitment End Date
- Clinical TrialIn-Person
What is this Study about?
The purpose of this study is to assess the efficacy of an oral medication, IGC-AD1 that is a natural THC-based (Tetrahydrocannabinol) formulation, administered in micro doses, twice a day, on symptomatological Agitation, in patients with mild to severe dementia from Alzheimer's.
Eligibility Criteria
60+
Diagnosis of Alzheimer's disease
Must have a study partnerRecruitment End Date
- Clinical TrialIn-Person
What is this Study about?
It is expected that the information collected during this study will be used in analyses and will be published/presented to the scientific community at meetings and in journals. This information may also be used as part of a submission to regulatory authorities around the world to support the approval of the study intervention for agitation in AD.
Eligibility Criteria
You are eligible to participate if you meet the following criteria:
• Age ≥ 55; females must be post-menopausal
• DSM-5 criteria for Major Neurocognitive Disorder due to AD; multiple etiologies (AD and vascular)
• sMMSE ≤ 24
• Clinically significant agitation based on IPA definition
• Stable cognition-enhancing medication for at least 3 months prior to study enrolment
• Availability of a caregiver to accompany participant to study visits and to participate in the study
• Ability to speak English
Recruitment End Date
- Clinical TrialOnline & In-Person
What is this Study about?
To examine the effects of a stress management program on well-being, stress, and cognition in family caregivers of someone with dementia or a related neurodegenerative disorder. We will be recruiting participants from 2023 - 2027.
Eligibility Criteria
- are a primary family caregiver of a person with dementia or a related neurodegenerative disorder.
- have access to a computer with high-speed internet; and feel comfortable using email and Zoom (a secure online meeting platform).
- have a video camera on your device. To ensure safety of participants during the program sessions, it is important that participants turn on their video camera. Keeping the video camera on is also important to build trust within the group sessions and when interacting with the researchers.
- are willing to be randomised to one of 3 groups, even if it is not your preferred group.
- are able to commit to a synchronous 8-week online group-based program (described below) and complete daily prescribed daily home practices.
- are able to commit to three assessment sessions: one baseline assessment, one post-program assessment, one 12-month follow-up assessment.
- agree to audio recording of interview sessions and portions of the assessment that require accurate verbal data collection.
- are able to provide blood samples, potentially after a 12-hour fast.
- are able to travel to a LifeLabs clinic for biomarker collection.
- agree to refrain from participating in new studies or programs during the 8-week study session.
- meet the screening criteria during the pre-screening interview.
- ability to speak English.
Recruitment End Date
Alzheimer Society of Canada
20 Eglinton Avenue West, 16th Floor
Toronto, Ontario M4R 1K8
Information and Referral Line: 1-855-705-4636
Email: research@alzheimer.ca
Charity registration number: 11878 4925 RR0001
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