Eligibility Criteria

You are eligible to participate if you:

• self-identify as Black (for example, African, Caribbean, Black Canadian, Afro-Latin, or another Black identity)
• are 18 years of age or older
• live in the Greater Toronto Area
• provide unpaid care to a family member living with dementia
• can speak and understand English well enough to take part in an interview

Eligibility Criteria

- are a substitute decision-maker of a person living with dementia in residential long-term care in Alberta or Ontario OR someone currently working with people living with dementia in residential long-term care in Alberta or Ontario;

- are a person who is 18 years of age or older;

- are a person able to read and write in English

Eligibility Criteria

• Are between 55-85 years of age

• Have a parent or sibling with Alzheimer’s disease or with dementia that may be due to Alzheimer’s disease (even if not diagnosed as such)

• Feel your memory is getting worse

• Get normal scores on tests of thinking and memory (will be done as part of the study)

• Are able to undergo brain MRI scans

• Have a study partner (friend or family member) willing to answer questionnaires about you

• Show increased brain signaling during the screening fMRI scan (Note: We anticipate that most people who sign up for the study will NOT show the increased brain activity levels required to qualify for the study treatment)

Eligibility Criteria

Les critères de base pour participer sont :

- Être âgé de 50 ans et +

- Avoir le français québécois comme langue principale

- Être droitier

- Avoir des inquiétudes concernant le fonctionnement de sa mémoir

Eligibility Criteria

• Are 50 years or older
• Have been diagnosed with mild to early-moderate Alzheimer's disease (including mixed dementia)
• Are medically stable and able to take part safely
• Experience mild to moderate depressive symptoms
• Feel comfortable using basic technology, such as a tablet or headset
• Have access to Wi-Fi and a smart device (such as a phone or tablet) for online sessions and study apps
• Have someone available to be present during all study sessions

Eligibility Criteria

To be eligible to participate in this study you must:

• be 60 years of age or older

• be living independently in the community

• have normal or corrected-to-normal vision and hearing

• read, write, and speak English fluently

• have feelings of memory decline in the past 5 years

• be able to exercise at a moderate pace for 60 minutes 3x/week receive clearance from a medical doctor (once deemed eligible) to participate in an exercise program

You are ineligible to participate in this study if you:

• cannot partake or commit to exercise training 3x/week for 26 weeks or have regularly engaged in exercise (more than once per week) over the past 3 months

• cannot partake or commit to consuming a daily supplement for 26 weeks or consumed nutritional supplements containing creatine monohydrate over the past 3 months

• have a known allergy to creatine monohydrate or dextrose (glucose, D-glucose)

• have been diagnosed with a neurological disorder (e.g., Alzheimer’s disease, Parkinson’s disease)

• have pre-existing kidney disease, heart disease, or liver abnormalities

• have one or more uncontrolled chronic or psychiatric conditions (e.g., hypertension, diabetes, depression, anxiety)

• are taking medication that may impact kidney function (e.g., non-steroidal anti-inflammatory drugs, such as ibuprofen and naproxen)

• are ineligible or uncomfortable with blood sampling.

Eligibility Criteria

You are eligible to participate if you are 60 years or older, have a confirmed diagnosis of Alzheimer’s disease, remain relatively independent in your day-to-day life, are able and willing to wear digital activity tracking technology to monitor daily activity patterns, and are able to provide informed consent and participate in study procedures. You are also eligible to participate if you are a partner/caregiver as a healthy control. 

Eligibility Criteria

1.) Diagnosed with Dementia and/or memory loss by a clinician

2.) Exhibit adequate oral communication skills and cognitive function

3.) Walk or stand with or without personnel or assistive devices

4.) Individuals must be greater than or equal to 50 years of age

Eligibility Criteria

- You are currently an unpaid caregiver for someone living with dementia in Canada

- You have been in this caregiving role for at least 1 year

- The person you care for may live with you, in their own home or in long-term care

- You must be able to complete an online questionnaire in English

- You have access to an internet connection and device