What is this Study about?

This study looks at how an at-home nature-based virtual reality (VR) program may help people living with Alzheimer’s Disease manage behavioural and psychological symptoms of dementia (BPSD), such as depression. Caregivers and/or study partners will have the option of taking part in the study and providing feedback regarding the VR intervention. This project will explore how virtual reality can be used as a non-pharmacological approach to prolong aging in place for individuals with BPSD, as BPSD contributes to rates of institutionalization.

What is this Study about?

The purpose of the study is to evaluate the effect of ALN-APP on measures of CAA disease progression and to characterize the safety, tolerability, and pharmacodynamics (PD) of ALN-APP in adult patients with sporadic CAA (sCAA) and Dutch-type CAA (D-CAA). The study will be conducted over 2 periods: a 24-month double-blind treatment period and an optional 18-month open-label extension (OLE) period. The estimated duration of study participation, inclusive of screening, treatment, and additional safety follow-up, is up to 50 months.

What is this Study about?

The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment [MCI] to mild dementia due to AD).

What is this Study about?

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disease.

What is this Study about?

The purpose of this study is to:Evaluate the safety and tolerability of intrathecal (IT) ALN-5288 in patients with Alzheimer's Disease (AD) and Evaluate the pharmacodynamic (PD) and pharmacokinetic (PK) effects of ALN-5288 after dose administration

What is this Study about?

This study investigates whether digital activity data collected from wearable and mobile devices can be used to understand changes in cognitive functioning associated with aging and neurological conditions. Participants’ daily movement patterns and activity behaviors will be monitored using advanced tracking technology that collects detailed spatial and temporal data. Researchers will analyze these patterns using computational methods to identify digital markers associated with cognitive functioning. 

What is this Study about?

McMaster University is conducting a study on the effects of brain stimulation in individuals aged 50 and older with dementia or memory loss. The research focuses on using repetitive transcranial magnetic stimulation (rTMS), a noninvasive technique that delivers magnetic pulses to the brain, to enhance cognitive function and balance. The goal is to extend the positive effects of brain stimulation in improving cognition and balance in individuals with dementia.

What is this Study about?

This study explores how adult day programs affect the lives of people living with dementia and their caregivers across several Canadian regions. Over time, we gather information about health, well-being, daily experiences, and quality of life of people living with dementia who attend day program and their caregivers. We also aim to learn about day programs themselves, such as their activities, staffing, challenges, and successes. By combining surveys, interviews, and focus groups, our program of research aims to understand what makes day programs helpful, where challenges exist, and how day program can better support families, and people who use them.

What is this Study about?

Assistive technology products are things that help you function or carry out activities more easily by yourself. Products could be any devices, equipment, instruments, or software. Examples could be mobile phone apps that provide calendar reminders, switches that turn off stoves, or walkers.

Assistive technology services are activities or resources that help you to use or maintain assistive technology products. Services refer to assessment, training, and maintenance that help with choosing, using, and repairing assistive technology products.

Getting these products and services means having to contact different organizations. If these products and services could be bundled as one unit, it may help persons with dementia get them more easily and potentially reduce costs. Right now, policymakers need more information about providing assistive technologies as bundles.

The purpose of the study is to learn about your experiences with accessing and using products and services for managing dementia. This information will help us to know what should be included in bundles.

For persons with dementia: We would like to interview you now to understand your past and current experiences. We would also like to interview you each year for up to three years (for three interviews) to see how your experiences change over time. You may leave at any time.

For care partners: The purpose of the surveys is to learn about your views and experiences with accessing and using products and services for managing dementia. This information will help us to know what should be included in bundles. If interested, you may also take part in longitudinal interviews (two interviews, one annually) after the initial survey in year one to see how your experiences changed over time. You may leave at any time.

For healthcare providers: The purpose of the surveys is to learn about your views and experiences with assisting persons with dementia and care partners to access and use products and services for managing dementia. This information will help us to know what should be included in bundles and how delivery may be improved. If interested, you may also take part 6 / 10 in longitudinal interviews (two interviews, one annually) after completing the initial survey in year one to see how your experiences changed over time. You may leave at any time.